منابع مشابه
Centromere identity is specified by a single centromeric nucleosome in budding yeast.
Chromosome segregation ensures that DNA is equally divided between daughter cells during each round of cell division. The centromere (CEN) is the specific locus on each chromosome that directs formation of the kinetochore, the multiprotein complex that interacts with the spindle microtubules to promote proper chromosomal alignment and segregation during mitosis. CENs are organized into a specia...
متن کاملSequences specify centromeric chromatin
n page 765, Ohzeki et al. present evidence for sequence specificity in assembling chromatin at mammalian centromeres. The sequence requirements imply that construction of centromeric chromatin is more than an epigenetic process. O Centromeric chromatin assembles at AT-rich repeats called ␣ satellite sequences, or alphoids. Type I alphoids contain boxes for the binding of CENP-B, one of several ...
متن کاملCentromeric chromatin gets loaded
Centromeric nucleosomes contain a histone H3 variant called centromere protein A (CENP-A) that is required for kinetochore assembly and chromosome segregation. Two new studies, Jansen et al. (see p. 795 of this issue) and Maddox et al. (see p. 757 of this issue), address when CENP-A is deposited at centromeres during the cell division cycle and identify an evolutionally conserved protein requir...
متن کاملCentromeric Chromatin: Histone deviants
Highly variant histones are targeted to specialized chromatin domains, such as the centromere where they have an essential role in the segregation of sister chromatids at mitosis.
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This paper explores the relevance of the Elaborated Social Identity Model of Crowd Behaviour and Procedural Justice Theory to an understanding of both the presence and absence of collective conflict during football (soccer) crowd events. It provides an analysis of data gathered during longitudinal ethnographic study of fans of Cardiff City Football Club—a group of supporters with a notorious hi...
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ژورنال
عنوان ژورنال: Nature Reviews Molecular Cell Biology
سال: 2012
ISSN: 1471-0072,1471-0080
DOI: 10.1038/nrm3356